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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST4
All Species:
9.7
Human Site:
S595
Identified Species:
23.7
UniProt:
Q8WYB5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYB5
NP_036462.2
2073
231378
S595
F
G
K
R
D
I
R
S
R
F
I
S
H
S
S
Chimpanzee
Pan troglodytes
XP_519734
1952
219524
I570
F
H
P
P
A
N
E
I
Y
R
K
N
N
I
S
Rhesus Macaque
Macaca mulatta
XP_001094798
1531
171769
C174
T
I
Y
C
Q
N
L
C
L
L
A
K
L
F
L
Dog
Lupus familis
XP_536397
2090
233726
S595
F
G
K
R
D
I
R
S
R
F
I
A
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRB7
1872
208521
K515
E
E
D
L
D
V
F
K
Q
A
Q
E
L
S
W
Rat
Rattus norvegicus
Q5TKR9
1998
223312
Y569
H
P
P
A
N
E
I
Y
R
K
N
N
I
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506182
2088
231546
S595
L
G
K
K
T
V
R
S
R
F
I
S
H
S
S
Chicken
Gallus gallus
XP_421609
2013
224707
N583
Y
R
R
K
E
V
R
N
R
F
I
P
R
A
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697383
2011
222731
L585
V
K
G
F
C
S
K
L
A
S
L
A
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786050
3082
341137
P706
D
D
P
N
N
E
D
P
N
D
A
D
V
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.2
33.1
94.2
N.A.
82.6
43.8
N.A.
83.6
81.4
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
27.3
Protein Similarity:
100
59.1
46.7
96.1
N.A.
86
58.3
N.A.
89.5
87.9
N.A.
70
N.A.
N.A.
N.A.
N.A.
40.6
P-Site Identity:
100
13.3
0
93.3
N.A.
13.3
13.3
N.A.
73.3
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
0
100
N.A.
26.6
26.6
N.A.
86.6
73.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
10
10
20
20
0
10
20
% A
% Cys:
0
0
0
10
10
0
0
10
0
0
0
0
0
0
10
% C
% Asp:
10
10
10
0
30
0
10
0
0
10
0
10
0
0
0
% D
% Glu:
10
10
0
0
10
20
10
0
0
0
0
10
0
0
0
% E
% Phe:
30
0
0
10
0
0
10
0
0
40
0
0
0
10
0
% F
% Gly:
0
30
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
10
0
0
0
0
0
0
0
0
0
0
30
0
0
% H
% Ile:
0
10
0
0
0
20
10
10
0
0
40
0
10
10
0
% I
% Lys:
0
10
30
20
0
0
10
10
0
10
10
10
0
0
0
% K
% Leu:
10
0
0
10
0
0
10
10
10
10
10
0
20
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
20
20
0
10
10
0
10
20
10
0
0
% N
% Pro:
0
10
30
10
0
0
0
10
0
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
10
10
20
0
0
40
0
50
10
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
10
0
30
0
10
0
20
10
60
40
% S
% Thr:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
30
0
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _